12/30/2024

Janusmed fosterpåverkan

Janusmed fosterpåverkan – Zopiclone Orion

Janusmed fosterpåverkan tillhandahåller bedömningar av eventuella risker för fostret, när en gravid kvinna använder olika läkemedel. Observera att texterna är generella, och att en bedömning måste göras i varje enskilt fall. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

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  1. Grigoriadis S, Alibrahim A, Mansfield JK, Sullovey A, Robinson GE. Hypnotic benzodiazepine receptor agonist exposure during pregnancy and the risk of congenital malformations and other adverse pregnancy outcomes: A systematic review and meta-analysis. Acta Psychiatr Scand. 2022 Apr 29. doi: 10.1111/acps.13441. Online ahead of print.

  2. United Kingdom Teratology Information Services (UKTIS). Hypnotic Benzodiazepine Receptor Agonists (HBRAs) use in pregnancy. UKTIS [www]. [updated 2018-02-01, cited 2022-07-07].

  3. Ban L, West J, Gibson JE, Fiaschi L, Sokal R, Doyle P et al. First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study. PLoS One. 2014;9:e100996.

  4. Wikner BN, Stiller CO, Bergman U, Asker C, Källén B. Use of benzodiazepines and benzodiazepine receptor agonists during pregnancy: neonatal outcome and congenital malformations. Pharmacoepidemiol Drug Saf 2007;16:1203-10.

  5. Wikner BN, Källén B. Are hypnotic benzodiazepine receptor agonists teratogenic in humans?. J Clin Psychopharmacol. 2011;31:356-9.

  6. Diav-Citrin O, Okotore B, Lucarelli K, Koren G. Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. Am J Perinatol. 1999;16:157-60.

  7. Sundbakk LM, Wood M, Gran JM, Nordeng H. Impact of prenatal exposure to benzodiazepines and z-hypnotics on behavioral problems at 5 years of age: A study from the Norwegian Mother and Child Cohort Study. PLoS One. 2019;14(6):e0217830.

  8. Lupattelli A, Chambers CD, Bandoli G, Handal M, Skurtveit S, Nordeng H. Association of Maternal Use of Benzodiazepines and Z-Hypnotics During Pregnancy With Motor and Communication Skills and Attention-Deficit/Hyperactivity Disorder Symptoms in Preschoolers. JAMA Netw Open. 2019;2(4):e191435.

  1. Grigoriadis S, Alibrahim A, Mansfield JK, Sullovey A, Robinson GE. Hypnotic benzodiazepine receptor agonist exposure during pregnancy and the risk of congenital malformations and other adverse pregnancy outcomes: A systematic review and meta-analysis. Acta Psychiatr Scand. 2022 Apr 29. doi: 10.1111/acps.13441. Online ahead of print.
  2. United Kingdom Teratology Information Services (UKTIS). Hypnotic Benzodiazepine Receptor Agonists (HBRAs) use in pregnancy. UKTIS [www]. [updated 2018-02-01, cited 2022-07-07].
  3. Ban L, West J, Gibson JE, Fiaschi L, Sokal R, Doyle P et al. First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study. PLoS One. 2014;9:e100996.
  4. Wikner BN, Stiller CO, Bergman U, Asker C, Källén B. Use of benzodiazepines and benzodiazepine receptor agonists during pregnancy: neonatal outcome and congenital malformations. Pharmacoepidemiol Drug Saf 2007;16:1203-10.
  5. Wikner BN, Källén B. Are hypnotic benzodiazepine receptor agonists teratogenic in humans?. J Clin Psychopharmacol. 2011;31:356-9.
  6. Diav-Citrin O, Okotore B, Lucarelli K, Koren G. Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. Am J Perinatol. 1999;16:157-60.
  7. Sundbakk LM, Wood M, Gran JM, Nordeng H. Impact of prenatal exposure to benzodiazepines and z-hypnotics on behavioral problems at 5 years of age: A study from the Norwegian Mother and Child Cohort Study. PLoS One. 2019;14(6):e0217830.
  8. Lupattelli A, Chambers CD, Bandoli G, Handal M, Skurtveit S, Nordeng H. Association of Maternal Use of Benzodiazepines and Z-Hypnotics During Pregnancy With Motor and Communication Skills and Attention-Deficit/Hyperactivity Disorder Symptoms in Preschoolers. JAMA Netw Open. 2019;2(4):e191435.