5/9/2026

Janusmed fosterpåverkan

Janusmed fosterpåverkan – Onbrez Breezhaler

Janusmed fosterpåverkan tillhandahåller bedömningar av eventuella risker för fostret, när en gravid kvinna använder olika läkemedel. Observera att texterna är generella, och att en bedömning måste göras i varje enskilt fall. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

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  1. Xu Z, Doust JA, Wilson LF, Dobson AJ, Dharmage SC, Mishra GD. Asthma severity and impact on perinatal outcomes: an updated systematic review and meta-analysis. BJOG. 2022;129(3):367-377.

  2. Abdullah K, Zhu J, Gershon A, Dell S, To T. Effect of asthma exacerbation during pregnancy in women with asthma: a population-based cohort study. Eur Respir J. 2020;55(2):1901335.

  3. Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia J et al. A meta-analysis of adverse perinatal outcomes in women with asthma. BJOG. 2011;118(11):1314-23.

  4. Robijn AL, Harvey SM, Jensen ME, Atkins S, Quek KJD, Wang G et al. Adverse neonatal outcomes in pregnant women with asthma: An updated systematic review and meta-analysis. Int J Gynaecol Obstet. 2024;166(2):596-606.

  5. Rejnö G, Lundholm C, Gong T, Larsson K, Saltvedt S, Almqvist C. Asthma during pregnancy in a population-based study--pregnancy complications and adverse perinatal outcomes. PLoS One. 2014;9(8):e104755.

  6. Murphy VE, Wang G, Namazy JA, Powell H, Gibson PG, Chambers C et al. The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta-analysis. BJOG. 2013;120(7):812-22.

  7. Kallen B, Rydhstroem H, Aberg A. Asthma during pregnancy - a population based study. Eur J Epidemiol 2000;16:167-71.

  8. Liu S, Wen SW, Demissie K, Marcoux S, Kramer MS. Maternal asthma and pregnancy outcomes: A retrospective cohort study. Am J Obstet Gynecol 2001;184:90-6.

  9. Garne E, Vinkel Hansen A, Morris J, Jordan S, Klungsøyr K, Engeland A et al. Risk of congenital anomalies after exposure to asthma medication in the first trimester of pregnancy - a cohort linkage study. BJOG. 2016;123(10):1609-18.

  10. Källén B, Otterblad Olausson P. Use of anti-asthmatic drugs during pregnancy. 3: Congenital malformations in the infants. Eur J Clin Pharmacol 2007;63:383-8.

  11. Jiao XF, Leal LF, Ducharme FM, Tse SM, Bérard A. First-trimester asthma controller medication use and major congenital malformation risk in offspring of women with asthma: A nationwide population-based cohort study. J Allergy Clin Immunol. 2026;Mar 31:S0091-6749(26)00218-6.

  12. Läkemedelsverket. Astma hos barn och vuxna – behandlings­rekommendation. Läkemedelsverket [www]. [updated 2023-03-27, cited 2026-04-20].

  13. NICE. Nice Guidelines Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN) . National Institute for Health and Care Excellence (NICE) [www]. [updated 2024-11-27, cited 2026-04-20].

  14. Briggs G, Towers CV, Forinash AB. Drugs in pregnancy and lactation: A reference guide to fetal and neonatal risk. 12th ed; 2021.

  15. Novartis Sverige AB. Onbrez Breeshaler. Produktresumé. EMA [www]. [updated 2025-11-18, cited 2026-04-20].

  16. Eltonsy S, Kettani FZ, Blais L. Beta2-agonists use during pregnancy and perinatal outcomes: a systematic review. Respir Med. 2014;108(1):9-33.

  1. Xu Z, Doust JA, Wilson LF, Dobson AJ, Dharmage SC, Mishra GD. Asthma severity and impact on perinatal outcomes: an updated systematic review and meta-analysis. BJOG. 2022;129(3):367-377.
  2. Abdullah K, Zhu J, Gershon A, Dell S, To T. Effect of asthma exacerbation during pregnancy in women with asthma: a population-based cohort study. Eur Respir J. 2020;55(2):1901335.
  3. Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia J et al. A meta-analysis of adverse perinatal outcomes in women with asthma. BJOG. 2011;118(11):1314-23.
  4. Robijn AL, Harvey SM, Jensen ME, Atkins S, Quek KJD, Wang G et al. Adverse neonatal outcomes in pregnant women with asthma: An updated systematic review and meta-analysis. Int J Gynaecol Obstet. 2024;166(2):596-606.
  5. Rejnö G, Lundholm C, Gong T, Larsson K, Saltvedt S, Almqvist C. Asthma during pregnancy in a population-based study--pregnancy complications and adverse perinatal outcomes. PLoS One. 2014;9(8):e104755.
  6. Murphy VE, Wang G, Namazy JA, Powell H, Gibson PG, Chambers C et al. The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta-analysis. BJOG. 2013;120(7):812-22.
  7. Kallen B, Rydhstroem H, Aberg A. Asthma during pregnancy - a population based study. Eur J Epidemiol 2000;16:167-71.
  8. Liu S, Wen SW, Demissie K, Marcoux S, Kramer MS. Maternal asthma and pregnancy outcomes: A retrospective cohort study. Am J Obstet Gynecol 2001;184:90-6.
  9. Garne E, Vinkel Hansen A, Morris J, Jordan S, Klungsøyr K, Engeland A et al. Risk of congenital anomalies after exposure to asthma medication in the first trimester of pregnancy - a cohort linkage study. BJOG. 2016;123(10):1609-18.
  10. Källén B, Otterblad Olausson P. Use of anti-asthmatic drugs during pregnancy. 3: Congenital malformations in the infants. Eur J Clin Pharmacol 2007;63:383-8.
  11. Jiao XF, Leal LF, Ducharme FM, Tse SM, Bérard A. First-trimester asthma controller medication use and major congenital malformation risk in offspring of women with asthma: A nationwide population-based cohort study. J Allergy Clin Immunol. 2026;Mar 31:S0091-6749(26)00218-6.
  12. Läkemedelsverket. Astma hos barn och vuxna – behandlings­rekommendation. Läkemedelsverket [www]. [updated 2023-03-27, cited 2026-04-20].
  13. NICE. Nice Guidelines Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN) . National Institute for Health and Care Excellence (NICE) [www]. [updated 2024-11-27, cited 2026-04-20].
  14. Briggs G, Towers CV, Forinash AB. Drugs in pregnancy and lactation: A reference guide to fetal and neonatal risk. 12th ed; 2021.
  15. Novartis Sverige AB. Onbrez Breeshaler. Produktresumé. EMA [www]. [updated 2025-11-18, cited 2026-04-20].
  16. Eltonsy S, Kettani FZ, Blais L. Beta2-agonists use during pregnancy and perinatal outcomes: a systematic review. Respir Med. 2014;108(1):9-33.