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Eussen SJ, Nilsen RM, Midttun Ø, Hustad S, IJssennagger N, Meyer K et al. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Br J Nutr. 2013;110(2):363-74.
Pfeiffer CM, Sternberg MR, Fazili Z, Lacher DA, Zhang M, Johnson CL et al. Folate status and concentrations of serum folate forms in the US population: National Health and Nutrition Examination Survey 2011-2. Br J Nutr. 2015;113(12):1965-77.
Folacin (folic acid). Summary of Product Characteristics. Medical Products Agency Sweden; 2018.
Bazzano LA, Reynolds K, Holder KN, He J. Effect of folic acid supplementation on risk of cardiovascular diseases: a meta-analysis of randomized controlled trials. JAMA. 2006;296(22):2720-6.
Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y et al. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet. 2007;369(9576):1876-1882.
Lee M, Hong KS, Chang SC, Saver JL. Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis. Stroke. 2010;41(6):1205-12.
Yang HT, Lee M, Hong KS, Ovbiagele B, Saver JL. Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Eur J Intern Med. 2012;23(8):745-54.
He K, Merchant A, Rimm EB, Rosner BA, Stampfer MJ, Willett WC et al. Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men. Stroke. 2004;35(1):169-74.
Larsson SC, Männistö S, Virtanen MJ, Kontto J, Albanes D, Virtamo J. Folate, vitamin B6, vitamin B12, and methionine intakes and risk of stroke subtypes in male smokers. Am J Epidemiol. 2008;167(8):954-61.
Al-Delaimy WK, Rexrode KM, Hu FB, Albert CM, Stampfer MJ, Willett WC et al. Folate intake and risk of stroke among women. Stroke. 2004;35(6):1259-63.
Vollset SE, Clarke R, Lewington S, Ebbing M, Halsey J, Lonn E et al. Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals. Lancet. 2013;381(9871):1029-36.
Qin T, Du M, Du H, Shu Y, Wang M, Zhu L. Folic acid supplements and colorectal cancer risk: meta-analysis of randomized controlled trials. Sci Rep. 2015;5(1):12044.
Du W, Li WY, Lu R, Fang JY. Folate and fiber in the prevention of colorectal cancer: between shadows and the light. World J Gastroenterol. 2010;16(8):921-6.
Kennedy DA, Stern SJ, Moretti M, Matok I, Sarkar M, Nickel C et al. Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis. Cancer Epidemiol. 2011;35(1):2-10.
Keum N, Giovannucci EL. Folic acid fortification and colorectal cancer risk. Am J Prev Med. 2014;46(3):S65-72.
Konings EJ, Goldbohm RA, Brants HA, Saris WH, van den Brandt PA. Intake of dietary folate vitamers and risk of colorectal carcinoma: results from The Netherlands Cohort Study. Cancer. 2002;95(7):1421-33.
La Vecchia C, Negri E, Pelucchi C, Franceschi S. Dietary folate and colorectal cancer. Int J Cancer. 2002;102(5):545-7.
Su LJ, Arab L. Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study. Ann Epidemiol. 2001;11(1):65-72.
Bird CL, Swendseid ME, Witte JS, Shikany JM, Hunt IF, Frankl HD et al. Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps. Cancer Epidemiol Biomarkers Prev. 1995;4(7):709-14.
Galeone C, Edefonti V, Parpinel M, Leoncini E, Matsuo K, Talamini R et al. Folate intake and the risk of oral cavity and pharyngeal cancer: a pooled analysis within the International Head and Neck Cancer Epidemiology Consortium. Int J Cancer. 2015;136(4):904-14.
Kawakita D, Lee YA, Gren LH, Buys SS, La Vecchia C, Hashibe M. The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort. Br J Cancer. 2018;118(2):299-306.
Zhang YF, Zhou L, Zhang HW, Hou AJ, Gao HF, Zhou YH. Association between folate intake and the risk of lung cancer: a dose-response meta-analysis of prospective studies. PLoS One. 2014;9(4):e93465.
Donnenfeld M, Deschasaux M, Latino-Martel P, Diallo A, Galan P, Hercberg S et al. Prospective association between dietary folate intake and skin cancer risk: results from the Supplémentation en Vitamines et Minéraux Antioxydants cohort. Am J Clin Nutr. 2015;102(2):471-8.
Peng Y, Dong B, Wang Z. Serum folate concentrations and all-cause, cardiovascular disease and cancer mortality: A cohort study based on 1999-2010 National Health and Nutrition Examination Survey (NHANES). Int J Cardiol. 2016;219(1):136-42.
Taylor MJ, Carney SM, Goodwin GM, Geddes JR. Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trials. J Psychopharmacol. 2004;18(2):251-6.
Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord. 2000;60(2):121-30.
Beydoun MA, Fanelli Kuczmarski MT, Beydoun HA, Shroff MR, Mason MA, Evans MK et al. The sex-specific role of plasma folate in mediating the association of dietary quality with depressive symptoms. J Nutr. 2010;140(2):338-47.
Beydoun MA, Shroff MR, Beydoun HA, Zonderman AB. Serum folate, vitamin B-12, and homocysteine and their association with depressive symptoms among US adults. Psychosom Med. 2010;72(9):862-73.
Ramos MI, Allen LH, Haan MN, Green R, Miller JW. Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification. Am J Clin Nutr. 2004;80(4):1024-8.
Nanri A, Mizoue T, Matsushita Y, Sasaki S, Ohta M, Sato M et al. Serum folate and homocysteine and depressive symptoms among Japanese men and women. Eur J Clin Nutr. 2010;64(3):289-96.
Murakami K, Mizoue T, Sasaki S, Ohta M, Sato M, Matsushita Y et al. Dietary intake of folate, other B vitamins, and omega-3 polyunsaturated fatty acids in relation to depressive symptoms in Japanese adults. Nutrition. 2008;24(2):140-7.
Skarupski KA, Tangney C, Li H, Ouyang B, Evans DA, Morris MC. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. Am J Clin Nutr. 2010;92(2):330-5.
Bentley TG, Willett WC, Weinstein MC, Kuntz KM. Population-level changes in folate intake by age, gender, and race/ethnicity after folic acid fortification. Am J Public Health. 2006;96(11):2040-7.
Steluti J, Selhub J, Paul L, Reginaldo C, Fisberg RM, Marchioni DML. An overview of folate status in a population-based study from São Paulo, Brazil and the potential impact of 10 years of national folic acid fortification policy. Eur J Clin Nutr. 2017;71(10):1173-1178.
Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2017 [cited 2018-12-06.]
- Eussen SJ, Nilsen RM, Midttun Ø, Hustad S, IJssennagger N, Meyer K et al. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Br J Nutr. 2013;110(2):363-74.
- Pfeiffer CM, Sternberg MR, Fazili Z, Lacher DA, Zhang M, Johnson CL et al. Folate status and concentrations of serum folate forms in the US population: National Health and Nutrition Examination Survey 2011-2. Br J Nutr. 2015;113(12):1965-77.
- Folacin (folic acid). Summary of Product Characteristics. Medical Products Agency Sweden; 2018.
- Bazzano LA, Reynolds K, Holder KN, He J. Effect of folic acid supplementation on risk of cardiovascular diseases: a meta-analysis of randomized controlled trials. JAMA. 2006;296(22):2720-6.
- Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y et al. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet. 2007;369(9576):1876-1882.
- Lee M, Hong KS, Chang SC, Saver JL. Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis. Stroke. 2010;41(6):1205-12.
- Yang HT, Lee M, Hong KS, Ovbiagele B, Saver JL. Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Eur J Intern Med. 2012;23(8):745-54.
- He K, Merchant A, Rimm EB, Rosner BA, Stampfer MJ, Willett WC et al. Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men. Stroke. 2004;35(1):169-74.
- Larsson SC, Männistö S, Virtanen MJ, Kontto J, Albanes D, Virtamo J. Folate, vitamin B6, vitamin B12, and methionine intakes and risk of stroke subtypes in male smokers. Am J Epidemiol. 2008;167(8):954-61.
- Al-Delaimy WK, Rexrode KM, Hu FB, Albert CM, Stampfer MJ, Willett WC et al. Folate intake and risk of stroke among women. Stroke. 2004;35(6):1259-63.
- Vollset SE, Clarke R, Lewington S, Ebbing M, Halsey J, Lonn E et al. Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals. Lancet. 2013;381(9871):1029-36.
- Qin T, Du M, Du H, Shu Y, Wang M, Zhu L. Folic acid supplements and colorectal cancer risk: meta-analysis of randomized controlled trials. Sci Rep. 2015;5(1):12044.
- Du W, Li WY, Lu R, Fang JY. Folate and fiber in the prevention of colorectal cancer: between shadows and the light. World J Gastroenterol. 2010;16(8):921-6.
- Kennedy DA, Stern SJ, Moretti M, Matok I, Sarkar M, Nickel C et al. Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis. Cancer Epidemiol. 2011;35(1):2-10.
- Keum N, Giovannucci EL. Folic acid fortification and colorectal cancer risk. Am J Prev Med. 2014;46(3):S65-72.
- Konings EJ, Goldbohm RA, Brants HA, Saris WH, van den Brandt PA. Intake of dietary folate vitamers and risk of colorectal carcinoma: results from The Netherlands Cohort Study. Cancer. 2002;95(7):1421-33.
- La Vecchia C, Negri E, Pelucchi C, Franceschi S. Dietary folate and colorectal cancer. Int J Cancer. 2002;102(5):545-7.
- Su LJ, Arab L. Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study. Ann Epidemiol. 2001;11(1):65-72.
- Bird CL, Swendseid ME, Witte JS, Shikany JM, Hunt IF, Frankl HD et al. Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps. Cancer Epidemiol Biomarkers Prev. 1995;4(7):709-14.
- Galeone C, Edefonti V, Parpinel M, Leoncini E, Matsuo K, Talamini R et al. Folate intake and the risk of oral cavity and pharyngeal cancer: a pooled analysis within the International Head and Neck Cancer Epidemiology Consortium. Int J Cancer. 2015;136(4):904-14.
- Kawakita D, Lee YA, Gren LH, Buys SS, La Vecchia C, Hashibe M. The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort. Br J Cancer. 2018;118(2):299-306.
- Zhang YF, Zhou L, Zhang HW, Hou AJ, Gao HF, Zhou YH. Association between folate intake and the risk of lung cancer: a dose-response meta-analysis of prospective studies. PLoS One. 2014;9(4):e93465.
- Donnenfeld M, Deschasaux M, Latino-Martel P, Diallo A, Galan P, Hercberg S et al. Prospective association between dietary folate intake and skin cancer risk: results from the Supplémentation en Vitamines et Minéraux Antioxydants cohort. Am J Clin Nutr. 2015;102(2):471-8.
- Peng Y, Dong B, Wang Z. Serum folate concentrations and all-cause, cardiovascular disease and cancer mortality: A cohort study based on 1999-2010 National Health and Nutrition Examination Survey (NHANES). Int J Cardiol. 2016;219(1):136-42.
- Taylor MJ, Carney SM, Goodwin GM, Geddes JR. Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trials. J Psychopharmacol. 2004;18(2):251-6.
- Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord. 2000;60(2):121-30.
- Beydoun MA, Fanelli Kuczmarski MT, Beydoun HA, Shroff MR, Mason MA, Evans MK et al. The sex-specific role of plasma folate in mediating the association of dietary quality with depressive symptoms. J Nutr. 2010;140(2):338-47.
- Beydoun MA, Shroff MR, Beydoun HA, Zonderman AB. Serum folate, vitamin B-12, and homocysteine and their association with depressive symptoms among US adults. Psychosom Med. 2010;72(9):862-73.
- Ramos MI, Allen LH, Haan MN, Green R, Miller JW. Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification. Am J Clin Nutr. 2004;80(4):1024-8.
- Nanri A, Mizoue T, Matsushita Y, Sasaki S, Ohta M, Sato M et al. Serum folate and homocysteine and depressive symptoms among Japanese men and women. Eur J Clin Nutr. 2010;64(3):289-96.
- Murakami K, Mizoue T, Sasaki S, Ohta M, Sato M, Matsushita Y et al. Dietary intake of folate, other B vitamins, and omega-3 polyunsaturated fatty acids in relation to depressive symptoms in Japanese adults. Nutrition. 2008;24(2):140-7.
- Skarupski KA, Tangney C, Li H, Ouyang B, Evans DA, Morris MC. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. Am J Clin Nutr. 2010;92(2):330-5.
- Bentley TG, Willett WC, Weinstein MC, Kuntz KM. Population-level changes in folate intake by age, gender, and race/ethnicity after folic acid fortification. Am J Public Health. 2006;96(11):2040-7.
- Steluti J, Selhub J, Paul L, Reginaldo C, Fisberg RM, Marchioni DML. An overview of folate status in a population-based study from São Paulo, Brazil and the potential impact of 10 years of national folic acid fortification policy. Eur J Clin Nutr. 2017;71(10):1173-1178.
- Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2017 [cited 2018-12-06.]