11/21/2024

Janusmed kön och genus

Janusmed kön och genus – Betolvidon

Janusmed kön och genus är ett kunskapsstöd som tillhandahåller information om köns- och genusaspekter på läkemedelsbehandling. Kunskapsstödet är avsedd främst för hälso- och sjukvårdspersonal. Texterna är generella och ska inte ses som behandlingsriktlinjer. Det är alltid behandlande läkare som ansvarar för patientens medicinering.

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Vitamin B12 (cyanokobolamin och derivat)

Vitamin B12 (cyanokobolamin och derivat)

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  1. Green R. Vitamin B12 deficiency from the perspective of a practicing hematologist. Blood. 2017;129(19):2603-2611.

  2. Hunt A, Harrington D, Robinson S. Vitamin B12 deficiency. BMJ. 2014;349(1):g5226.

  3. Stabler SP. Clinical practice Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60.

  4. Kumar N. Neurologic aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120(1):915-26.

  5. vant Sant P, Küsters PF, Harthoorn-Lasthuizen EJ. Dependency of MCV and haemoglobin concentration on plasma vitamin B12 levels in relation to sex and age. Clin Lab Haematol. 1997;19(1):27-31.

  6. Harris E, Macpherson H, Pipingas A. Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults. Nutrients. 2015;7(5):3796-812.

  7. Castelli MC, Friedman K, Sherry J, Brazzillo K, Genoble L, Bhargava P et al. Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study. Clin Ther. 2011;33(3):358-371e2.

  8. Bolaman Z, Kadikoylu G, Yukselen V, Yavasoglu I, Barutca S, Senturk T. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Clin Ther. 2003;25(12):3124-34.

  9. Dangour AD, Allen E, Clarke R, Elbourne D, Fletcher AE, Letley L et al. Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. Am J Clin Nutr. 2015;102(3):639-47.

  10. Rogne T, Tielemans MJ, Chong MF, Yajnik CS, Krishnaveni GV, Poston L et al. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. Am J Epidemiol. 2017;185(3):212-223.

  11. Eussen SJ, Nilsen RM, Midttun Ø, Hustad S, IJssennagger N, Meyer K et al. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Br J Nutr. 2013;110(2):363-74.

  12. González-Gross M, Benser J, Breidenassel C, Albers U, Huybrechts I, Valtueña J et al. Gender and age influence blood folate, vitamin B12, vitamin B6, and homocysteine levels in European adolescents: the Helena Study. Nutr Res. 2012;32(11):817-26.

  13. Seppälä J, Koponen H, Kautiainen H, Eriksson JG, Kampman O, Leiviskä J et al. Association between vitamin b12 levels and melancholic depressive symptoms: a Finnish population-based study. BMC Psychiatry. 2013;13(1):145.

  14. Björkegren K, Svärdsudd K. Serum cobalamin, folate, methylmalonic acid and total homocysteine as vitamin B12 and folate tissue deficiency markers amongst elderly Swedes--a population-based study. J Intern Med. 2001;249(5):423-32.

  15. Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL et al. Vitamin B12 deficiency in the aged: a population-based study. Age Ageing. 2007;36(2):177-83.

  16. Dhonukshe-Rutten RA, Lips M, de Jong N, Chin A Paw MJ, Hiddink GJ, van Dusseldorp M et al. Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men. J Nutr. 2003;133(3):801-7.

  17. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2017 [cited 2018-12-06.]

  1. Green R. Vitamin B12 deficiency from the perspective of a practicing hematologist. Blood. 2017;129(19):2603-2611.
  2. Hunt A, Harrington D, Robinson S. Vitamin B12 deficiency. BMJ. 2014;349(1):g5226.
  3. Stabler SP. Clinical practice Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60.
  4. Kumar N. Neurologic aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120(1):915-26.
  5. vant Sant P, Küsters PF, Harthoorn-Lasthuizen EJ. Dependency of MCV and haemoglobin concentration on plasma vitamin B12 levels in relation to sex and age. Clin Lab Haematol. 1997;19(1):27-31.
  6. Harris E, Macpherson H, Pipingas A. Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults. Nutrients. 2015;7(5):3796-812.
  7. Castelli MC, Friedman K, Sherry J, Brazzillo K, Genoble L, Bhargava P et al. Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study. Clin Ther. 2011;33(3):358-371e2.
  8. Bolaman Z, Kadikoylu G, Yukselen V, Yavasoglu I, Barutca S, Senturk T. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Clin Ther. 2003;25(12):3124-34.
  9. Dangour AD, Allen E, Clarke R, Elbourne D, Fletcher AE, Letley L et al. Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. Am J Clin Nutr. 2015;102(3):639-47.
  10. Rogne T, Tielemans MJ, Chong MF, Yajnik CS, Krishnaveni GV, Poston L et al. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. Am J Epidemiol. 2017;185(3):212-223.
  11. Eussen SJ, Nilsen RM, Midttun Ø, Hustad S, IJssennagger N, Meyer K et al. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Br J Nutr. 2013;110(2):363-74.
  12. González-Gross M, Benser J, Breidenassel C, Albers U, Huybrechts I, Valtueña J et al. Gender and age influence blood folate, vitamin B12, vitamin B6, and homocysteine levels in European adolescents: the Helena Study. Nutr Res. 2012;32(11):817-26.
  13. Seppälä J, Koponen H, Kautiainen H, Eriksson JG, Kampman O, Leiviskä J et al. Association between vitamin b12 levels and melancholic depressive symptoms: a Finnish population-based study. BMC Psychiatry. 2013;13(1):145.
  14. Björkegren K, Svärdsudd K. Serum cobalamin, folate, methylmalonic acid and total homocysteine as vitamin B12 and folate tissue deficiency markers amongst elderly Swedes--a population-based study. J Intern Med. 2001;249(5):423-32.
  15. Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL et al. Vitamin B12 deficiency in the aged: a population-based study. Age Ageing. 2007;36(2):177-83.
  16. Dhonukshe-Rutten RA, Lips M, de Jong N, Chin A Paw MJ, Hiddink GJ, van Dusseldorp M et al. Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men. J Nutr. 2003;133(3):801-7.
  17. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2017 [cited 2018-12-06.]