5/8/2026

Janusmed kön och genus

Janusmed kön och genus – Abilify

Janusmed kön och genus är ett kunskapsstöd som tillhandahåller information om köns- och genusaspekter på läkemedelsbehandling. Kunskapsstödet är avsedd främst för hälso- och sjukvårdspersonal. Texterna är generella och ska inte ses som behandlingsriktlinjer. Det är alltid behandlande läkare som ansvarar för patientens medicinering.

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C C
C C

Aripiprazol

Aripiprazol

Klass : C

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  1. Food and Drug Administration (FDA). Abilify (aripiprazole) drug label. Drugs@FDA [www]. [updated 2002-11-15, cited 2026-03-31].

  2. Hoekstra S, Bartz-Johannessen C, Sinkeviciute I, Reitan SK, Kroken RA, Løberg EM et al. Sex differences in antipsychotic efficacy and side effects in schizophrenia spectrum disorder: results from the BeSt InTro study. NPJ Schizophr. 2021;7(1):39.

  3. Belmonte C, Ochoa D, Román M, Saiz-Rodríguez M, Wojnicz A, Gómez-Sánchez CI et al. Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2018;122(6):596-605.

  4. Abilify (aripiprazole). Summary of Product Characteristics. European Medicines Agency (EMA) [updated 2026-01-12, 2026-03-31]

  5. Stephen Marder, MD and T Scott Stroup, MD, MPH. Pharmacotherapy for schizophrenia: Side effect management. UpToDate [www]. [updated 2019-10-16, cited 2020-06-30].

  6. Crespo-Facorro B, Ortiz-Garcia de la Foz V, Suarez-Pinilla P, Valdizan EM, Pérez-Iglesias R, Amado-Señaris JA, Garcia-Unzueta MT, Labad J, Correll C, Ayesa-Arriola R. Effects of aripiprazole, quetiapine and ziprasidone on plasma prolactin levels in individuals with first episode nonaffective psychosis: Analysis of a randomized open-label 1 year study. Schizophr Res. 2017;189:134-141.

  7. Veselinović T, Schorn H, Vernaleken IB, Schiffl K, Klomp M, Gründer G. Impact of different antidopaminergic mechanisms on the dopaminergic control of prolactin secretion. J Clin Psychopharmacol. 2011;31(2):214-220.

  8. Öztürk Yalçın Z, Bayraktar İ, Kaşıkcı M, Yalçın N, Özçelik Eroğlu E, Yağcıoğlu AEA et al. Beyond dose: Antipsychotic risk categories and sex-specific vulnerability to hyperprolactinemia in real-world longitudinal care. Psychoneuroendocrinology. 2026;188:107838.

  9. Zucker I, Prendergast BJ. Sex differences in pharmacokinetics predict adverse drug reactions in women. Biol Sex Differ. 2020;11(1):32.

  10. Qi F, Tian L, Diao H, Zhao S, Li F, Zhang Y et al. Adverse events associated with four atypical antipsychotics used as augmentation treatment for major depressive disorder: A pharmacovigilance study based on the FAERS database. J Affect Disord. 2025;388:119435.

  11. Stamoula E, Stamatellos VP, Vavilis T, Dardalas I, Papazisis G. Weight gain, gender, and antipsychotics: a disproportionality analysis of the FDA Adverse Event Reporting System database (FAERS). Expert Opin Drug Saf. 2024;23(2):239-245.

  12. McCall KL, Leppien EE, Piper BJ, Falco BM, Fleck KK, Govel JC et al. Second-Generation Antipsychotic-Associated Serious Adverse Events in Women: An Analysis of a National Pharmacoepidemiologic Database. J Clin Psychopharmacol. 2025;45(2):111-115.

  13. Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2025 [cited 2026-03-20.]

  1. Food and Drug Administration (FDA). Abilify (aripiprazole) drug label. Drugs@FDA [www]. [updated 2002-11-15, cited 2026-03-31].
  2. Hoekstra S, Bartz-Johannessen C, Sinkeviciute I, Reitan SK, Kroken RA, Løberg EM et al. Sex differences in antipsychotic efficacy and side effects in schizophrenia spectrum disorder: results from the BeSt InTro study. NPJ Schizophr. 2021;7(1):39.
  3. Belmonte C, Ochoa D, Román M, Saiz-Rodríguez M, Wojnicz A, Gómez-Sánchez CI et al. Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2018;122(6):596-605.
  4. Abilify (aripiprazole). Summary of Product Characteristics. European Medicines Agency (EMA) [updated 2026-01-12, 2026-03-31]
  5. Stephen Marder, MD and T Scott Stroup, MD, MPH. Pharmacotherapy for schizophrenia: Side effect management. UpToDate [www]. [updated 2019-10-16, cited 2020-06-30].
  6. Crespo-Facorro B, Ortiz-Garcia de la Foz V, Suarez-Pinilla P, Valdizan EM, Pérez-Iglesias R, Amado-Señaris JA, Garcia-Unzueta MT, Labad J, Correll C, Ayesa-Arriola R. Effects of aripiprazole, quetiapine and ziprasidone on plasma prolactin levels in individuals with first episode nonaffective psychosis: Analysis of a randomized open-label 1 year study. Schizophr Res. 2017;189:134-141.
  7. Veselinović T, Schorn H, Vernaleken IB, Schiffl K, Klomp M, Gründer G. Impact of different antidopaminergic mechanisms on the dopaminergic control of prolactin secretion. J Clin Psychopharmacol. 2011;31(2):214-220.
  8. Öztürk Yalçın Z, Bayraktar İ, Kaşıkcı M, Yalçın N, Özçelik Eroğlu E, Yağcıoğlu AEA et al. Beyond dose: Antipsychotic risk categories and sex-specific vulnerability to hyperprolactinemia in real-world longitudinal care. Psychoneuroendocrinology. 2026;188:107838.
  9. Zucker I, Prendergast BJ. Sex differences in pharmacokinetics predict adverse drug reactions in women. Biol Sex Differ. 2020;11(1):32.
  10. Qi F, Tian L, Diao H, Zhao S, Li F, Zhang Y et al. Adverse events associated with four atypical antipsychotics used as augmentation treatment for major depressive disorder: A pharmacovigilance study based on the FAERS database. J Affect Disord. 2025;388:119435.
  11. Stamoula E, Stamatellos VP, Vavilis T, Dardalas I, Papazisis G. Weight gain, gender, and antipsychotics: a disproportionality analysis of the FDA Adverse Event Reporting System database (FAERS). Expert Opin Drug Saf. 2024;23(2):239-245.
  12. McCall KL, Leppien EE, Piper BJ, Falco BM, Fleck KK, Govel JC et al. Second-Generation Antipsychotic-Associated Serious Adverse Events in Women: An Analysis of a National Pharmacoepidemiologic Database. J Clin Psychopharmacol. 2025;45(2):111-115.
  13. Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2025 [cited 2026-03-20.]