11/18/2025

Janusmed kön och genus

Janusmed kön och genus – Tirzepatid

Janusmed kön och genus är ett kunskapsstöd som tillhandahåller information om köns- och genusaspekter på läkemedelsbehandling. Kunskapsstödet är avsedd främst för hälso- och sjukvårdspersonal. Texterna är generella och ska inte ses som behandlingsriktlinjer. Det är alltid behandlande läkare som ansvarar för patientens medicinering.

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C C
C C

Tirzepatid

Tirzepatid

Klass : C

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  1. Carlsson S, Andersson T, Jansson S, Nyström T, Rolandsson O, Wei Y. Increasing incidence of early-onset type 2 diabetes in Sweden 2006-2021. Eur J Public Health. 2025;:.

  2. Folkhälsomyndigheten. Övervikt och obesitas, interaktivt faktablad. Folkhälsomyndigheten [www]. [updated 2025-03-17, cited 2025-10-24].

  3. Cooper AJ, Gupta SR, Moustafa AF, Chao AM. Sex/Gender Differences in Obesity Prevalence, Comorbidities, and Treatment. Curr Obes Rep. 2021;10(4):458-466.

  4. Censin JC, Peters SAE, Bovijn J, Ferreira T, Pulit SL, Mägi R et al. Causal relationships between obesity and the leading causes of death in women and men. PLoS Genet. 2019;15(10):e1008405.

  5. Statistikdatabas för operationer. Stockholm: Socialstyrelsen. 2024 [cited 2025-10-24.]

  6. Assessment report - Mounjaro (tirzepatide). European Medicines Agency (EMA) [www]. [updated 2022-07-21, cited 2025-10-24].

  7. De Block C, Peleshok J, Wilding JPH, Kwan AYM, Rasouli N, Maldonado JM et al. Post Hoc Analysis of SURPASS-1 to -5: Efficacy and Safety of Tirzepatide in Adults with Type 2 Diabetes are Independent of Baseline Characteristics. Diabetes Ther. 2025;16(1):43-71.

  8. Plat AW, Rasouli N, Peleshok J, Sapin H, Wilding J. Change in Body Weight from Baseline with Tirzepatide: Sex Subgroup Analysis of the SURPASS Studies. Diabetes 2022;71 (supplement_1):720-P.

  9. Małecki MT, Batterham RL, Sattar N, Levine JA, Rodríguez Á, Bergman BK et al. Predictors of ≥15% Weight Reduction and Associated Changes in Cardiometabolic Risk Factors With Tirzepatide in Adults With Type 2 Diabetes in SURPASS 1-4. Diabetes Care. 2023;46(12):2292-2299.

  10. Garcia LE, Chao A, Mojdami D, Forrester T, Taylor R, Chigusta F et al. Body weight reduction with tirzepatide by sex: a subgroup analysis of the SURMOUNT clinical trials (abstract). EASD Annual Meeting [cited 2025-10-28]

  11. Ou Y, Cui Z, Lou S, Zhu C, Chen J, Zhou L et al. Analysis of tirzepatide in the US FDA adverse event reporting system (FAERS): a focus on overall patient population and sex-specific subgroups. Front Pharmacol. 2024;15:1463657.

  12. Mounjaro (tirzepatide). Summary of Product Characteristics. European Medicines Agency (EMA) [updated 2025-01-11, cited 2025-10-28]

  13. Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2024 [cited 2025-04-23.]

  1. Carlsson S, Andersson T, Jansson S, Nyström T, Rolandsson O, Wei Y. Increasing incidence of early-onset type 2 diabetes in Sweden 2006-2021. Eur J Public Health. 2025;:.
  2. Folkhälsomyndigheten. Övervikt och obesitas, interaktivt faktablad. Folkhälsomyndigheten [www]. [updated 2025-03-17, cited 2025-10-24].
  3. Cooper AJ, Gupta SR, Moustafa AF, Chao AM. Sex/Gender Differences in Obesity Prevalence, Comorbidities, and Treatment. Curr Obes Rep. 2021;10(4):458-466.
  4. Censin JC, Peters SAE, Bovijn J, Ferreira T, Pulit SL, Mägi R et al. Causal relationships between obesity and the leading causes of death in women and men. PLoS Genet. 2019;15(10):e1008405.
  5. Statistikdatabas för operationer. Stockholm: Socialstyrelsen. 2024 [cited 2025-10-24.]
  6. Assessment report - Mounjaro (tirzepatide). European Medicines Agency (EMA) [www]. [updated 2022-07-21, cited 2025-10-24].
  7. De Block C, Peleshok J, Wilding JPH, Kwan AYM, Rasouli N, Maldonado JM et al. Post Hoc Analysis of SURPASS-1 to -5: Efficacy and Safety of Tirzepatide in Adults with Type 2 Diabetes are Independent of Baseline Characteristics. Diabetes Ther. 2025;16(1):43-71.
  8. Plat AW, Rasouli N, Peleshok J, Sapin H, Wilding J. Change in Body Weight from Baseline with Tirzepatide: Sex Subgroup Analysis of the SURPASS Studies. Diabetes 2022;71 (supplement_1):720-P.
  9. Małecki MT, Batterham RL, Sattar N, Levine JA, Rodríguez Á, Bergman BK et al. Predictors of ≥15% Weight Reduction and Associated Changes in Cardiometabolic Risk Factors With Tirzepatide in Adults With Type 2 Diabetes in SURPASS 1-4. Diabetes Care. 2023;46(12):2292-2299.
  10. Garcia LE, Chao A, Mojdami D, Forrester T, Taylor R, Chigusta F et al. Body weight reduction with tirzepatide by sex: a subgroup analysis of the SURMOUNT clinical trials (abstract). EASD Annual Meeting [cited 2025-10-28]
  11. Ou Y, Cui Z, Lou S, Zhu C, Chen J, Zhou L et al. Analysis of tirzepatide in the US FDA adverse event reporting system (FAERS): a focus on overall patient population and sex-specific subgroups. Front Pharmacol. 2024;15:1463657.
  12. Mounjaro (tirzepatide). Summary of Product Characteristics. European Medicines Agency (EMA) [updated 2025-01-11, cited 2025-10-28]
  13. Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2024 [cited 2025-04-23.]