11/21/2024

Janusmed amning

Janusmed amning – merkaptopurinmonohydrat

Janusmed amning tillhandahåller generella rekommendationer om huruvida ett friskt fullgånget spädbarn kan ammas när modern använder olika läkemedel. Observera att prematura och/eller sjuka spädbarn alltid kräver särskilda överväganden. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

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2 2
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Merkaptopurin

Merkaptopurin

Klass : 2

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  1. Moretti ME, Verjee Z, Ito S, Koren G. Breast-feeding during maternal use of azathioprine. Ann Pharmacother 2006;40(12):2269-2272

  2. Sau A, Clarke S, Bass J, Kaiser A, Marinaki A, Nelson-Piercy C. Azathioprine and breastfeeding: is it safe? BJOG 2007;114(4):498-501

  3. Coulam CB, Moyer TP, Jiang NS, Zincke H. Breast-feeding after renal transplantation. Transplant Proc 1982;14(3):605-9.

  4. Christensen LA, Dahlerup JF, Schmiegelow K. Excretion of azathioprine metabolites in maternal milk. Gut 2005;54(Suppl VII):A45

  5. Christensen LA, Dahlerup JF, Nielsen MJ, Fallingborg JF, Schmiegelow K. Azathioprine treatment during lactation. Aliment Pharmacol Ther. 2008;28(10):1209-13.

  6. Kane SV, Present DH. Metabolites to immunomodulators are not detected in brest milk. Am J Gastroenterol 2004;99(10 Suppl):246-247

  7. Gardiner SJ, Gearry RB, Roberts RL, Zhang M, Barclay ML, Begg EJ. Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs. Br J Clin Pharmacol 2006;62(4):453-6.

  8. Gardiner SJ, Gearry RB, Roberts RL, Zhang M, Barclay ML, Begg EJ. Comment: Breast-feeding during maternal use of azathioprine. Ann Pharmacother 2007;41(4):719-20.

  9. Bernard N, Garayt C, Chol F, Vial T, Descotes J. Prospective clinical and biological follow-up of three breastfed babies from azathioprine-treated mothers. Fundam Clin Pharmacol 2007;21(Suppl 1):62-3.

  10. Khare MM, Lott J, Currie A, Howarth E. Is it safe to continue azathioprine in breast feeding mothers? J Obstet Gynaecol 2003;23(Suppl 1):S48

  11. Grekas DM, Vasiliou SS, Lazarides AN. Immunosuppressive therapy and breast-feeding after renal transplantation. Nephron 1984;37(1):68

  12. Nyberg G, Haljamae U, Frisenette-Fich C, Wennergren M, Kjellmer I. Breast-feeding during treatment with cyclosporine. Transplantation 1998;65(2):253-255.

  13. Azathioprine. Lactmed (drugs and lactation database). Tillgänglig via: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT

  14. Angelberger S, Reinisch W, Messerschmidt A, Miehsler W, Novacek G, Vogelsang H et al. Long-term follow-up of babies exposed to azathioprine in utero and via breastfeeding. J Crohns Colitis. 2011;5:95-100.

  15. Zelinkova Z, De Boer IP, Van Dijke MJ, Kuipers EJ, Van Der Woude CJ. Azathioprine treatment during lactation. Aliment Pharmacol Ther. 2009;30:90-1; author reply 91.

  16. Munoz-Flores-Thiagarajan KD, Easterling T, Davis C, Bond EF. Breast-feeding by a cyclosporine-treated mother. Obstet Gynecol 2001;97(5 Pt 2):816-818.

  17. Werner M, Björnsson E, Prytz H, Lindgren S, Almer S, Broomé U et al. Autoimmune hepatitis among fertile women: strategies during pregnancy and breastfeeding?. Scand J Gastroenterol. 2007;42(8):986-91.

  18. de Meij TG, Jharap B, Kneepkens CM, van Bodegraven AA, de Boer NK, Dutch Initiative on Crohn and Colitis. Long-term follow-up of children exposed intrauterine to maternal thiopurine therapy during pregnancy in females with inflammatory bowel disease. Aliment Pharmacol Ther. 2013;38(1):38-43.

  19. Bernard N, Gouraud A, Paret N, Cottin J, Descotes J, Vial T . Azathioprine and breastfeeding: long-term follow-up. Fundam Clin Pharmacol. 2013;27(Suppl 1:12):Abstract 05-03.

  20. Beswick L, Shukla D, Friedman A, Fazal M, Florin T, Andrews J, et al. National audit: Assessing the use and safety of allopurinol thiopurine co-therapy in pregnant females with inflammatory bowel disease. J Gastroenterol Hepatol. 2016;31(Suppl 2):128-129.

  21. Ter Horst P, Smolders EJ, den Besten D. Mercaptopurine and Metabolites in Breast Milk. Breastfeed Med. 2019.

  1. Moretti ME, Verjee Z, Ito S, Koren G. Breast-feeding during maternal use of azathioprine. Ann Pharmacother 2006;40(12):2269-2272
  2. Sau A, Clarke S, Bass J, Kaiser A, Marinaki A, Nelson-Piercy C. Azathioprine and breastfeeding: is it safe? BJOG 2007;114(4):498-501
  3. Coulam CB, Moyer TP, Jiang NS, Zincke H. Breast-feeding after renal transplantation. Transplant Proc 1982;14(3):605-9.
  4. Christensen LA, Dahlerup JF, Schmiegelow K. Excretion of azathioprine metabolites in maternal milk. Gut 2005;54(Suppl VII):A45
  5. Christensen LA, Dahlerup JF, Nielsen MJ, Fallingborg JF, Schmiegelow K. Azathioprine treatment during lactation. Aliment Pharmacol Ther. 2008;28(10):1209-13.
  6. Kane SV, Present DH. Metabolites to immunomodulators are not detected in brest milk. Am J Gastroenterol 2004;99(10 Suppl):246-247
  7. Gardiner SJ, Gearry RB, Roberts RL, Zhang M, Barclay ML, Begg EJ. Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs. Br J Clin Pharmacol 2006;62(4):453-6.
  8. Gardiner SJ, Gearry RB, Roberts RL, Zhang M, Barclay ML, Begg EJ. Comment: Breast-feeding during maternal use of azathioprine. Ann Pharmacother 2007;41(4):719-20.
  9. Bernard N, Garayt C, Chol F, Vial T, Descotes J. Prospective clinical and biological follow-up of three breastfed babies from azathioprine-treated mothers. Fundam Clin Pharmacol 2007;21(Suppl 1):62-3.
  10. Khare MM, Lott J, Currie A, Howarth E. Is it safe to continue azathioprine in breast feeding mothers? J Obstet Gynaecol 2003;23(Suppl 1):S48
  11. Grekas DM, Vasiliou SS, Lazarides AN. Immunosuppressive therapy and breast-feeding after renal transplantation. Nephron 1984;37(1):68
  12. Nyberg G, Haljamae U, Frisenette-Fich C, Wennergren M, Kjellmer I. Breast-feeding during treatment with cyclosporine. Transplantation 1998;65(2):253-255.
  13. Azathioprine. Lactmed (drugs and lactation database). Tillgänglig via: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT
  14. Angelberger S, Reinisch W, Messerschmidt A, Miehsler W, Novacek G, Vogelsang H et al. Long-term follow-up of babies exposed to azathioprine in utero and via breastfeeding. J Crohns Colitis. 2011;5:95-100.
  15. Zelinkova Z, De Boer IP, Van Dijke MJ, Kuipers EJ, Van Der Woude CJ. Azathioprine treatment during lactation. Aliment Pharmacol Ther. 2009;30:90-1; author reply 91.
  16. Munoz-Flores-Thiagarajan KD, Easterling T, Davis C, Bond EF. Breast-feeding by a cyclosporine-treated mother. Obstet Gynecol 2001;97(5 Pt 2):816-818.
  17. Werner M, Björnsson E, Prytz H, Lindgren S, Almer S, Broomé U et al. Autoimmune hepatitis among fertile women: strategies during pregnancy and breastfeeding?. Scand J Gastroenterol. 2007;42(8):986-91.
  18. de Meij TG, Jharap B, Kneepkens CM, van Bodegraven AA, de Boer NK, Dutch Initiative on Crohn and Colitis. Long-term follow-up of children exposed intrauterine to maternal thiopurine therapy during pregnancy in females with inflammatory bowel disease. Aliment Pharmacol Ther. 2013;38(1):38-43.
  19. Bernard N, Gouraud A, Paret N, Cottin J, Descotes J, Vial T . Azathioprine and breastfeeding: long-term follow-up. Fundam Clin Pharmacol. 2013;27(Suppl 1:12):Abstract 05-03.
  20. Beswick L, Shukla D, Friedman A, Fazal M, Florin T, Andrews J, et al. National audit: Assessing the use and safety of allopurinol thiopurine co-therapy in pregnant females with inflammatory bowel disease. J Gastroenterol Hepatol. 2016;31(Suppl 2):128-129.
  21. Ter Horst P, Smolders EJ, den Besten D. Mercaptopurine and Metabolites in Breast Milk. Breastfeed Med. 2019.

Innehållet senast uppdaterat 11/7/2024