Kvetiapin
Kvetiapin
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Alzen Depot, Biquetan, Ketipinor, Kvetiapin Ebb, Quetiapin 1A Farma, Q......
Alzen Depot, Biquetan, Ketipinor, Kvetiapin Ebb, Quetiapin 1A Farma, Quetiapin Actavis, Quetiapin Aristo, Quetiapin Arrow, Quetiapin Ebb, Quetiapin Fair-Med, Quetiapin Hexal, Quetiapin Krka, Quetiapin Medical Valley, Quetiapin Orion, Quetiapin Sandoz, Quetiapin Stada, Quetiapine Accord, Quetiapine Teva, Seroquel, Seroquel DepotATC-koder
N05AH04
N05AH04Substanser
kvetiapin, kvetiapinfumarat
kvetiapin, kvetiapinfumaratRekommendation för hälso- och sjukvården
Risken för barnet anses vara låg vid terapeutiska doser. Eventuella långtidseffekter av antipsykotiska läkemedel på CNS-utvecklingen är dock okända.
Risken för barnet anses vara låg vid terapeutiska doser. Eventuella långtidseffekter av antipsykotiska läkemedel på CNS-utvecklingen är dock okända.Råd till allmänheten
Går bra att använda under amning
Går bra att använda under amningBakgrund
Passerar över till bröstmjölk i låg grad. Baserat på data från 14 ammande kvinnor kan den relativa barndosen beräknas vara som högst 0,5 % (1–10,18). Koncentrationer upp till 15 ng/mL har uppmätts hos två barn (16). Inga negativa effekter har rapporterats hos 27 ammade barn (1-7,9-17).
Passerar över till bröstmjölk i låg grad. Baserat på data från 14 ammande kvinnor kan den relativa barndosen beräknas vara som högst 0,5 % (1–10,18). Koncentrationer upp till 15 ng/mL har uppmätts hos två barn (16). Inga negativa effekter har rapporterats hos 27 ammade barn (1-7,9-17).Referenser
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Lee A, Giesbrecht E, Dunn E, Ito S. Excretion of quetiapine in breast milk. Am J Psychiatry. 2004;161(9):1715-6.
Misri S, Corral M, Wardrop AA, Kendrick K. Quetiapine augmentation in lactation: a series of case reports. J Clin Psychopharmacol. 2006;26(5):508-11.
Rampono J, Kristensen JH, Ilett KF, Hackett LP, Kohan R. Quetiapine and breast feeding. Ann Pharmacother. 2007;41(4):711-4.
Krüninger U, Meltzer V, Heinke C, Herpich S, Schreiber W. Pregnancy and lactation under treatment with quetiapine. Psychiatrische Praxis 2007;34(Suppl 1):S75-S76
Balke LD. Quetiapine effective in the treatment of bipolar affective disorder during pregnancy. World J Biol Psychiatry 2001;(2):303S. Abstract P021-15.
Seppälä J. Quetiapine ('Seroquel') is effective and well tolerated in the treatment of psychotic depression during breast-feeding. Int J Neuropsychopharmacol 2004;7 (Suppl 1)(S245):Abstract P01.431.
Kruninger U, Meltzer V, Hiemke C. Schwangerschaft und Stillzeit unter Behandlung mit Quetipine - eine kasuistik. Psychiatr Prax. 2007;34(Suppl 1):S75-6.
L.Var, I.Ince, A.Topuzoglu, A.Yildiz. Management of postpartum manic episode without cessation of breastfeeding: a longitudinal follow up of drug excretion into breast milk. Eur Neuropsychopharmacol 2013;23 Suppl 2:382.
Aydin B, Nayir T, Sahin S, Yildiz A. Olanzapine and quetiapine use during breastfeeding: excretion into breast milk and safe breastfeeding strategy. J Clin Psychopharmacol. 2015;35:206-8.
Pastol J, Le Marois M, Guilhaumou R, Blin O, Belzeaux R. Measuring drug concentrations in breast milk to improve therapeutic monitoring and patient adherence in bipolar disorder: A case report. Aust N Z J Psychiatry. 2021;2(5):48674211010340.
Levesque S, Riley C. Fetal exposure to lamotrigine and quetiapine in two consecutive pregnancies. Arch Womens Ment Health. 2017;20(1):237-239.
Newport DJ, Ritchie JC, Knight BT, Glover BA, Zach EB, Stowe ZN. Venlafaxine in human breast milk and nursing infant plasma: determination of exposure. J Clin Psychiatry. 2009;70(9):1304-10.
Sinha SK, Kishore MT, Thippeswamy H, Kommu JVS, Chandra PS. Adverse effects and short-term developmental outcomes of infants exposed to atypical antipsychotics during breastfeeding. Indian J Psychiatry. 2021;63(1):52-57.
Uguz F. Prophylactic use of olanzapine and quetiapine from pregnancy to the postpartum period in women with bipolar disorder: a case series. J Matern Fetal Neonatal Med. 2017;30(21):2569-2571.
Van Boekholt AA, Hartong EG, Huntjens-Fleuren H, Grootens KP, Semmekrot BA. Quetiapine concentrations during exclusive breastfeeding and maternal quetiapine use. Ann Pharmacother. 2015;49(6):743-4.
Gentile S. Quetiapine-fluvoxamine combination during pregnancy and while breastfeeding. Arch Womens Ment Health. 2006;3(9):158-9.
Ritz S. Quetiapine monotherapy in post-partum onset bipolar disorder with a mixed affective state . EurNeuropsychopharmacol . 2005;1(15):407.
Konishi T, Kitahiro Y, Fujiwara N, Yamamoto K, Hashimoto M, Ito T et al. Pharmacokinetics of Brexpiprazole, Quetiapine, Risperidone, and Its Active Metabolite Paliperidone in a Postpartum Woman and Her Baby. Ther Drug Monit. 2024.
- Lee A, Giesbrecht E, Dunn E, Ito S. Excretion of quetiapine in breast milk. Am J Psychiatry. 2004;161(9):1715-6.
- Misri S, Corral M, Wardrop AA, Kendrick K. Quetiapine augmentation in lactation: a series of case reports. J Clin Psychopharmacol. 2006;26(5):508-11.
- Rampono J, Kristensen JH, Ilett KF, Hackett LP, Kohan R. Quetiapine and breast feeding. Ann Pharmacother. 2007;41(4):711-4.
- Krüninger U, Meltzer V, Heinke C, Herpich S, Schreiber W. Pregnancy and lactation under treatment with quetiapine. Psychiatrische Praxis 2007;34(Suppl 1):S75-S76
- Balke LD. Quetiapine effective in the treatment of bipolar affective disorder during pregnancy. World J Biol Psychiatry 2001;(2):303S. Abstract P021-15.
- Seppälä J. Quetiapine ('Seroquel') is effective and well tolerated in the treatment of psychotic depression during breast-feeding. Int J Neuropsychopharmacol 2004;7 (Suppl 1)(S245):Abstract P01.431.
- Kruninger U, Meltzer V, Hiemke C. Schwangerschaft und Stillzeit unter Behandlung mit Quetipine - eine kasuistik. Psychiatr Prax. 2007;34(Suppl 1):S75-6.
- L.Var, I.Ince, A.Topuzoglu, A.Yildiz. Management of postpartum manic episode without cessation of breastfeeding: a longitudinal follow up of drug excretion into breast milk. Eur Neuropsychopharmacol 2013;23 Suppl 2:382.
- Aydin B, Nayir T, Sahin S, Yildiz A. Olanzapine and quetiapine use during breastfeeding: excretion into breast milk and safe breastfeeding strategy. J Clin Psychopharmacol. 2015;35:206-8.
- Pastol J, Le Marois M, Guilhaumou R, Blin O, Belzeaux R. Measuring drug concentrations in breast milk to improve therapeutic monitoring and patient adherence in bipolar disorder: A case report. Aust N Z J Psychiatry. 2021;2(5):48674211010340.
- Levesque S, Riley C. Fetal exposure to lamotrigine and quetiapine in two consecutive pregnancies. Arch Womens Ment Health. 2017;20(1):237-239.
- Newport DJ, Ritchie JC, Knight BT, Glover BA, Zach EB, Stowe ZN. Venlafaxine in human breast milk and nursing infant plasma: determination of exposure. J Clin Psychiatry. 2009;70(9):1304-10.
- Sinha SK, Kishore MT, Thippeswamy H, Kommu JVS, Chandra PS. Adverse effects and short-term developmental outcomes of infants exposed to atypical antipsychotics during breastfeeding. Indian J Psychiatry. 2021;63(1):52-57.
- Uguz F. Prophylactic use of olanzapine and quetiapine from pregnancy to the postpartum period in women with bipolar disorder: a case series. J Matern Fetal Neonatal Med. 2017;30(21):2569-2571.
- Van Boekholt AA, Hartong EG, Huntjens-Fleuren H, Grootens KP, Semmekrot BA. Quetiapine concentrations during exclusive breastfeeding and maternal quetiapine use. Ann Pharmacother. 2015;49(6):743-4.
- Gentile S. Quetiapine-fluvoxamine combination during pregnancy and while breastfeeding. Arch Womens Ment Health. 2006;3(9):158-9.
- Ritz S. Quetiapine monotherapy in post-partum onset bipolar disorder with a mixed affective state . EurNeuropsychopharmacol . 2005;1(15):407.
- Konishi T, Kitahiro Y, Fujiwara N, Yamamoto K, Hashimoto M, Ito T et al. Pharmacokinetics of Brexpiprazole, Quetiapine, Risperidone, and Its Active Metabolite Paliperidone in a Postpartum Woman and Her Baby. Ther Drug Monit. 2024.
Författare
Klinisk farmakologi, Karolinska Universitetssjukhuset för Hälso- och sjukvårdsförvaltningen, Region Stockholm. Janusmed amning uppdateras kvartalsvis.
Klinisk farmakologi, Karolinska Universitetssjukhuset för Hälso- och sjukvårdsförvaltningen, Region Stockholm. Janusmed amning uppdateras kvartalsvis.För patienter och allmänhet
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Innehållet senast uppdaterat 2024-11-07