7/12/2025

Janusmed amning

Janusmed amning – Pro-Epanutin

Janusmed amning tillhandahåller generella rekommendationer om huruvida ett friskt fullgånget spädbarn kan ammas när modern använder olika läkemedel. Observera att prematura och/eller sjuka spädbarn alltid kräver särskilda överväganden. Om du inte är medicinskt utbildad, läs först vår information för patienter och allmänhet.

För att komma till startsidan för Janusmed amning och för att göra sökningar klicka här.

Tillbaka till index
2 2
2 2

Fosfenytoin

Fosfenytoin

Klass : 2

Visa all info

Skriv ut

Kontakta oss

  1. Horning MG, Stillwell WG, Nowlin J, Letratanangkoon K, Stillwell RN, Hill RM. Identification and quantification of drugs and drug metabilites in human breast milk using GC-MS_COM methods. Mod Probl Paediat. 1975;15:73-79.

  2. Steen B, Rane A, Lönnerholm G, Falk O, Elwin CE, Sjöqvist F. Phenytoin excretion in human breast milk and plasma levels in nursed infants. Ther Drug Monit 1982;4(4):331-334

  3. Rane A, Garle M, Borgå O, Sjöqvist F. Plasma disappearance of transplacentally transferred diphenylhydantoin in the newborn studied by mass fragmentography. Clin Pharmacol Ther 1974;15(1):39-45

  4. Söderman P, Matheson I. Clonazepam in breast milk. Eur J Pediatr 1988;147(2):212-213

  5. Shimoyama R, Ohkubo T, Sugawara K, Ogasawara T, Ozaki T, Kagiya A et al. Monitoring of phenytoin in human breast milk, maternal plasma and cord blood plasma by solid-phase extraction and liquid chromatography. J Pharm Biomed Anal 1998;17(4-5):863-869

  6. Mirkin BL. Diphenylhydantoin: placental transport, fetal localization, neonatal metabolism, and possible teratogenic effects. J Pediatr 1971;78(2):329-337

  7. Meyer FP, Quednow B, Potrafki A, Walther H. [Pharmacokinetics of anticonvulsants in the perinatal period]. Zentralbl Gynakol 1988;110(19):1195-1205

  8. Granstrom ML, Bardy AH, Hiilesmaa VK. Prolonged feeding difficulties of infants of primidone mothers during neonatal period: preliminary results from the Helsinki study. In: Janz D, Dam M, Bossi L, Helge H, Richens A, Schmidt D, editors. Epilepsy, pregnancy and the child. New York: Raven Press; 1982. 357-358.

  9. Meador KJ, Baker GA, Browning N, Clayton-Smith J, Combs-Cantrell DT, Cohen M et al. Effects of breastfeeding in children of women taking antiepileptic drugs. Neurology. 2010;75:1954-60.

  10. Meador KJ, Baker GA, Browning N, Cohen MJ, Bromley RL, Clayton-Smith J et al. Breastfeeding in children of women taking antiepileptic drugs: cognitive outcomes at age 6 years. JAMA Pediatr. 2014;168:729-36.

  11. Kaneko S, Sato T, Suzuki K. The levels of anticonvulsants in breast milk. Br J Clin Pharmacol 1979;7(6):624-627

  12. Kok TH, Taitz LS, Bennett MJ, Holt DW. Drowsiness due to clemastine transmitted in breast milk. Lancet 1982;1(8277):914-915.

  13. Finch E, Lorber J. Methaemoglobinaemia in the newborn probably due to phenytoin excreted in human milk. J Obstet Gynaecol Br Emp 1954;61(6):833-4.

  1. Horning MG, Stillwell WG, Nowlin J, Letratanangkoon K, Stillwell RN, Hill RM. Identification and quantification of drugs and drug metabilites in human breast milk using GC-MS_COM methods. Mod Probl Paediat. 1975;15:73-79.
  2. Steen B, Rane A, Lönnerholm G, Falk O, Elwin CE, Sjöqvist F. Phenytoin excretion in human breast milk and plasma levels in nursed infants. Ther Drug Monit 1982;4(4):331-334
  3. Rane A, Garle M, Borgå O, Sjöqvist F. Plasma disappearance of transplacentally transferred diphenylhydantoin in the newborn studied by mass fragmentography. Clin Pharmacol Ther 1974;15(1):39-45
  4. Söderman P, Matheson I. Clonazepam in breast milk. Eur J Pediatr 1988;147(2):212-213
  5. Shimoyama R, Ohkubo T, Sugawara K, Ogasawara T, Ozaki T, Kagiya A et al. Monitoring of phenytoin in human breast milk, maternal plasma and cord blood plasma by solid-phase extraction and liquid chromatography. J Pharm Biomed Anal 1998;17(4-5):863-869
  6. Mirkin BL. Diphenylhydantoin: placental transport, fetal localization, neonatal metabolism, and possible teratogenic effects. J Pediatr 1971;78(2):329-337
  7. Meyer FP, Quednow B, Potrafki A, Walther H. [Pharmacokinetics of anticonvulsants in the perinatal period]. Zentralbl Gynakol 1988;110(19):1195-1205
  8. Granstrom ML, Bardy AH, Hiilesmaa VK. Prolonged feeding difficulties of infants of primidone mothers during neonatal period: preliminary results from the Helsinki study. In: Janz D, Dam M, Bossi L, Helge H, Richens A, Schmidt D, editors. Epilepsy, pregnancy and the child. New York: Raven Press; 1982. 357-358.
  9. Meador KJ, Baker GA, Browning N, Clayton-Smith J, Combs-Cantrell DT, Cohen M et al. Effects of breastfeeding in children of women taking antiepileptic drugs. Neurology. 2010;75:1954-60.
  10. Meador KJ, Baker GA, Browning N, Cohen MJ, Bromley RL, Clayton-Smith J et al. Breastfeeding in children of women taking antiepileptic drugs: cognitive outcomes at age 6 years. JAMA Pediatr. 2014;168:729-36.
  11. Kaneko S, Sato T, Suzuki K. The levels of anticonvulsants in breast milk. Br J Clin Pharmacol 1979;7(6):624-627
  12. Kok TH, Taitz LS, Bennett MJ, Holt DW. Drowsiness due to clemastine transmitted in breast milk. Lancet 1982;1(8277):914-915.
  13. Finch E, Lorber J. Methaemoglobinaemia in the newborn probably due to phenytoin excreted in human milk. J Obstet Gynaecol Br Emp 1954;61(6):833-4.

Innehållet senast uppdaterat 5/7/2025