10/18/2024

Janusmed sex and gender

Janusmed sex and gender – metoprolol succinate

Janusmed Sex and Gender is a knowledge database providing information on sex and gender aspects of drug treatment. The knowledge database is primarily intended to be used by physicians and healthcare professionals. The texts are general and should not be considered as treatment guidelines. The individual patient’s physician is responsible for the patient’s drug treatment.

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Metoprolol

Metoprolol

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  1. Luzier AB, Killian A, Wilton JH, Wilson MF, Forrest A, Kazierad DJ. Gender-related effects on metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers. Clin Pharmacol Ther. 1999;66:594-601.

  2. Sharma A, Pibarot P, Pilote S, Dumesnil JG, Arsenault M, Bélanger PM et al. Toward optimal treatment in women: the effect of sex on metoprolol-diphenhydramine interaction. J Clin Pharmacol. 2010;50(2):214-25.

  3. Schaaf LJ, Campbell SC, Mayersohn MB, Vagedes T, Perrier DG. Influence of smoking and gender on the disposition kinetics of metoprolol. Eur J Clin Pharmacol. 1987;33:355-61.

  4. Kapsargo (metoprolol). DailyMed [www]. US National Library of Medicine. [updated 2023-04-12, cited 2023-05-03].

  5. Hendriksen LC, Omes-Smit G, Koch BCP, Ikram MA, Stricker BH, Visser LE. Sex-Based Difference in the Effect of Metoprolol on Heart Rate and Bradycardia in a Population-Based Setting. J Pers Med. 2022;12(6):.

  6. Fredman RM. Metoprolol for hypertension Open trial in general practice. Med J Aust. 1982;2(8):378-80.

  7. Ghali JK, Piña IL, Gottlieb SS, Deedwania PC, Wikstrand JC, MERIT-HF Study Group. Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). Circulation. 2002;105:1585-91.

  8. Olsson G, Wikstrand J, Warnold I, Manger Cats V, McBoyle D, Herlitz J et al. Metoprolol-induced reduction in postinfarction mortality: pooled results from five double-blind randomized trials. Eur Heart J. 1992;13:28-32.

  9. Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2022 [cited 2023-03-02.]

  1. Luzier AB, Killian A, Wilton JH, Wilson MF, Forrest A, Kazierad DJ. Gender-related effects on metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers. Clin Pharmacol Ther. 1999;66:594-601.
  2. Sharma A, Pibarot P, Pilote S, Dumesnil JG, Arsenault M, Bélanger PM et al. Toward optimal treatment in women: the effect of sex on metoprolol-diphenhydramine interaction. J Clin Pharmacol. 2010;50(2):214-25.
  3. Schaaf LJ, Campbell SC, Mayersohn MB, Vagedes T, Perrier DG. Influence of smoking and gender on the disposition kinetics of metoprolol. Eur J Clin Pharmacol. 1987;33:355-61.
  4. Kapsargo (metoprolol). DailyMed [www]. US National Library of Medicine. [updated 2023-04-12, cited 2023-05-03].
  5. Hendriksen LC, Omes-Smit G, Koch BCP, Ikram MA, Stricker BH, Visser LE. Sex-Based Difference in the Effect of Metoprolol on Heart Rate and Bradycardia in a Population-Based Setting. J Pers Med. 2022;12(6):.
  6. Fredman RM. Metoprolol for hypertension Open trial in general practice. Med J Aust. 1982;2(8):378-80.
  7. Ghali JK, Piña IL, Gottlieb SS, Deedwania PC, Wikstrand JC, MERIT-HF Study Group. Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). Circulation. 2002;105:1585-91.
  8. Olsson G, Wikstrand J, Warnold I, Manger Cats V, McBoyle D, Herlitz J et al. Metoprolol-induced reduction in postinfarction mortality: pooled results from five double-blind randomized trials. Eur Heart J. 1992;13:28-32.
  9. Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2022 [cited 2023-03-02.]