10/18/2024

Janusmed sex and gender

Janusmed sex and gender – cyanocobalamin (Co-57)

Janusmed Sex and Gender is a knowledge database providing information on sex and gender aspects of drug treatment. The knowledge database is primarily intended to be used by physicians and healthcare professionals. The texts are general and should not be considered as treatment guidelines. The individual patient’s physician is responsible for the patient’s drug treatment.

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Vitamin B12 (cyanocobalamin and derivates)

Vitamin B12 (cyanocobalamin and derivates)

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  1. Green R. Vitamin B12 deficiency from the perspective of a practicing hematologist. Blood. 2017;129(19):2603-2611.

  2. Hunt A, Harrington D, Robinson S. Vitamin B12 deficiency. BMJ. 2014;349(1):g5226.

  3. Stabler SP. Clinical practice Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60.

  4. Kumar N. Neurologic aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120(1):915-26.

  5. vant Sant P, Küsters PF, Harthoorn-Lasthuizen EJ. Dependency of MCV and haemoglobin concentration on plasma vitamin B12 levels in relation to sex and age. Clin Lab Haematol. 1997;19(1):27-31.

  6. Harris E, Macpherson H, Pipingas A. Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults. Nutrients. 2015;7(5):3796-812.

  7. Castelli MC, Friedman K, Sherry J, Brazzillo K, Genoble L, Bhargava P et al. Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study. Clin Ther. 2011;33(3):358-371e2.

  8. Bolaman Z, Kadikoylu G, Yukselen V, Yavasoglu I, Barutca S, Senturk T. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Clin Ther. 2003;25(12):3124-34.

  9. Dangour AD, Allen E, Clarke R, Elbourne D, Fletcher AE, Letley L et al. Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. Am J Clin Nutr. 2015;102(3):639-47.

  10. Rogne T, Tielemans MJ, Chong MF, Yajnik CS, Krishnaveni GV, Poston L et al. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. Am J Epidemiol. 2017;185(3):212-223.

  11. Eussen SJ, Nilsen RM, Midttun Ø, Hustad S, IJssennagger N, Meyer K et al. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Br J Nutr. 2013;110(2):363-74.

  12. González-Gross M, Benser J, Breidenassel C, Albers U, Huybrechts I, Valtueña J et al. Gender and age influence blood folate, vitamin B12, vitamin B6, and homocysteine levels in European adolescents: the Helena Study. Nutr Res. 2012;32(11):817-26.

  13. Seppälä J, Koponen H, Kautiainen H, Eriksson JG, Kampman O, Leiviskä J et al. Association between vitamin b12 levels and melancholic depressive symptoms: a Finnish population-based study. BMC Psychiatry. 2013;13(1):145.

  14. Björkegren K, Svärdsudd K. Serum cobalamin, folate, methylmalonic acid and total homocysteine as vitamin B12 and folate tissue deficiency markers amongst elderly Swedes--a population-based study. J Intern Med. 2001;249(5):423-32.

  15. Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL et al. Vitamin B12 deficiency in the aged: a population-based study. Age Ageing. 2007;36(2):177-83.

  16. Dhonukshe-Rutten RA, Lips M, de Jong N, Chin A Paw MJ, Hiddink GJ, van Dusseldorp M et al. Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men. J Nutr. 2003;133(3):801-7.

  17. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2017 [cited 2018-12-06.]

  1. Green R. Vitamin B12 deficiency from the perspective of a practicing hematologist. Blood. 2017;129(19):2603-2611.
  2. Hunt A, Harrington D, Robinson S. Vitamin B12 deficiency. BMJ. 2014;349(1):g5226.
  3. Stabler SP. Clinical practice Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60.
  4. Kumar N. Neurologic aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120(1):915-26.
  5. vant Sant P, Küsters PF, Harthoorn-Lasthuizen EJ. Dependency of MCV and haemoglobin concentration on plasma vitamin B12 levels in relation to sex and age. Clin Lab Haematol. 1997;19(1):27-31.
  6. Harris E, Macpherson H, Pipingas A. Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults. Nutrients. 2015;7(5):3796-812.
  7. Castelli MC, Friedman K, Sherry J, Brazzillo K, Genoble L, Bhargava P et al. Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study. Clin Ther. 2011;33(3):358-371e2.
  8. Bolaman Z, Kadikoylu G, Yukselen V, Yavasoglu I, Barutca S, Senturk T. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Clin Ther. 2003;25(12):3124-34.
  9. Dangour AD, Allen E, Clarke R, Elbourne D, Fletcher AE, Letley L et al. Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. Am J Clin Nutr. 2015;102(3):639-47.
  10. Rogne T, Tielemans MJ, Chong MF, Yajnik CS, Krishnaveni GV, Poston L et al. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. Am J Epidemiol. 2017;185(3):212-223.
  11. Eussen SJ, Nilsen RM, Midttun Ø, Hustad S, IJssennagger N, Meyer K et al. North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Br J Nutr. 2013;110(2):363-74.
  12. González-Gross M, Benser J, Breidenassel C, Albers U, Huybrechts I, Valtueña J et al. Gender and age influence blood folate, vitamin B12, vitamin B6, and homocysteine levels in European adolescents: the Helena Study. Nutr Res. 2012;32(11):817-26.
  13. Seppälä J, Koponen H, Kautiainen H, Eriksson JG, Kampman O, Leiviskä J et al. Association between vitamin b12 levels and melancholic depressive symptoms: a Finnish population-based study. BMC Psychiatry. 2013;13(1):145.
  14. Björkegren K, Svärdsudd K. Serum cobalamin, folate, methylmalonic acid and total homocysteine as vitamin B12 and folate tissue deficiency markers amongst elderly Swedes--a population-based study. J Intern Med. 2001;249(5):423-32.
  15. Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL et al. Vitamin B12 deficiency in the aged: a population-based study. Age Ageing. 2007;36(2):177-83.
  16. Dhonukshe-Rutten RA, Lips M, de Jong N, Chin A Paw MJ, Hiddink GJ, van Dusseldorp M et al. Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men. J Nutr. 2003;133(3):801-7.
  17. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2017 [cited 2018-12-06.]