10/18/2024

Janusmed sex and gender

Janusmed sex and gender – Levetiracetam

Janusmed Sex and Gender is a knowledge database providing information on sex and gender aspects of drug treatment. The knowledge database is primarily intended to be used by physicians and healthcare professionals. The texts are general and should not be considered as treatment guidelines. The individual patient’s physician is responsible for the patient’s drug treatment.

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Levetiracetam

Levetiracetam

Class : A

  1. Keppra (levetiracetam). Summary of Product Characteristics. Swedish Medical Products Agency (MPA) [updated 2019-03-01, cited 2019-10-09].
  2. Keppra (levetiracetam). DailyMed [www]. US National Library of Medicine. [updated 2017-11-07, cited 2019-10-09].
  3. US Food and Drug Administration. Statistical Review(s) - KEPPRA (levetiracetam). Drugs@FDA [www]. [updated 2001-08-30, cited 2019-10-09].
  4. US Food and Drug Administration. Clinical Pharmacology Biopharmaceutics Review - KEPPRA (levetiracetam). Drugs@FDA [www]. [updated 2001-08-30, cited 2019-10-09].
  5. Alzueta, N, Ortega, A, and Aldaz, A. Influence of Sex, Age, and Weight on Levetiracetam Pharmacokinetics. Ther Drug Monit. 2018;40(5):628-634.
  6. Glauser TA, Mitchell WG, Weinstock A, Bebin M, Chen D, Coupez R et al. Pharmacokinetics of levetiracetam in infants and young children with epilepsy. Epilepsia. 2007;48:1117-22.
  7. Artemiadis AK, Lambrinoudaki I, Voskou P, Tsivgoulis G, Safouris A, Bougea A et al. Preliminary evidence for gender effects of levetiracetam monotherapy duration on bone health of patients with epilepsy. Epilepsy Behav. 2016;55:84-6.
  8. Svalheim S, Taubøll E, Luef G, Lossius A, Rauchenzauner M, Sandvand F et al. Differential effects of levetiracetam, carbamazepine, and lamotrigine on reproductive endocrine function in adults. Epilepsy Behav. 2009;16:281-7.
  9. Rauchenzauner M, Bitsche G, Svalheim S, Tauboll E, Haberlandt E, Wildt L et al. Effects of levetiracetam and valproic acid monotherapy on sex-steroid hormones in prepubertal children--results from a pilot study. Epilepsy Res. 2010;88:264-8.
  10. Wu D, Chen L, Ji F, Si Y, Sun H. The effects of oxcarbazepine, levetiracetam, and lamotrigine on semen quality, sexual function, and sex hormones in male adults with epilepsy. Epilepsia. 2018;59(7):1344-1350.
  11. Yogarajah M, Mula M. Sexual Dysfunction in Epilepsy and the Role of Anti-Epileptic Drugs. Curr Pharm Des. 2017;23(37):5649-5661.
  12. Ceylan M , Yalcin A, Bayraktutan OF , Karabulut I, Sonkaya AR. Effects of levetiracetam monotherapy on sperm parameters and sex hormones: Data from newly diagnosed patients with epilepsy. Epilepsia. 2016;41:70-4.
  13. Tomson T, Landmark CJ, Battino D. Antiepileptic drug treatment in pregnancy: changes in drug disposition and their clinical implications. Epilepsia. 2013;54:405-14.
  14. Mintzer S, Trinka E, Kraemer G, Chervoneva I, Werhahn KJ. Impact of carbamazepine, lamotrigine, and levetiracetam on vascular risk markers and lipid-lowering agents in the elderly. Epilepsia. 2018;59(10):1899-1907.
  15. Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2019 [cited 2020-03-10.]